NEPHROPROTECTIVE EFFECT OF GRAPE WINE IN THE RAT WITH EXPERIMENTAL DIABETES MELLITUS
DOI: http://dx.doi.org/10.30970/sbi.0303.060
Abstract
It was established that polyphenols of red and white grape wines completely or partially normalize kidney weight to body weight ratio, the level of nitrotyrosine modified proteins and activity of poly-ADP-ribose polymerase-1 in the kidney of rats with diabetes mellitus, compared with diabetic animals without wine consumptions.
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1. Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes, 2005; 54(6): 1615-1625. | |
| |
2. Cole A.R., Astell A., Green C., Sutherland C. Molecular connexions between dementia and diabetes. Neurosci. Biobehav, 2007; 31(7): 1046-1063. | |
| |
3. Daglia M., Papetti A., Grisoli P. et al. Antibacterial activity of red and white wine against oral streptococci. J. Agric. Food. Chem, 2007; 55(13): 5038-5042. | |
| |
4. Das S., Santani D.D., Dhalla N.S. Experimental evidence for the cardioprotective effects of red wine. Exp. Clin. Cardiol, 2007; 12(1): 5-10. | |
| |
5. Drel V.R., Pacher P., Stevens M.J., Obrosova I.G. Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells. Free Radic. Biol. Med, 2006; 40(8): 1454-1465. | |
| |
6. Gouni-Berthold I., Krone W. Diabetic ketoacidosis and hyperosmolar hyperglycemic state. Med. Klin. (Munich), 2006; 101 (Suppl 1): 100-105. | |
| |
7. Kitabchi A.E., Umpierrez G.E., Fisher J.N. et al. Thirty years of personal experience in hyperglycemic crises: diabetic ketoacidosis and hyperglycemic hyperosmolar state. J. Clin. Endocrinol. Metab, 2008; 93(5): 1541-1552. | |
| |
8. Landau D., Israel E., Rivkis I. et al. The effect of growth hormone on the development of diabetic kidney disease in rats. Nephrol. Dial. Transplant, 2003; 18(4): 694-702. | |
| |
9. Marshall S.M. Recent advances in diabetic nephropathy. Postgrad. Med. J, 2004; 80(949): 624-633. | |
| |
10. Montilla P., Barcos M., Munoz M.C. et al. Red wine prevents brain oxidative stress and nephropathy in streptozotocin-induced diabetic rats. J. Biochem. Mol. Biol, 2005; 38(5): 539-544. | |
| |
11. Negre-Salvayre A., Salvayre R., Augé N. et al. Hyperglycemia and glycation in diabetic complications. Antioxid. Redox. Signal, 2009; 11(12): 3071-3109. | |
| |
12. Pacher P., Obrosova I.G., Mabley J.G., Szabó C. Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies. Curr. Med. Chem, 2005; 12(3): 267-275. | |
| |
13. Peterson G.L. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem, 1977; 83(2): 346-356. | |
| |
14. Rajesh M., Mukhopadhyay P., Godlewski G. et al. Poly(ADP-ribose)polymerase inhibition decreases angiogenesis. Biochem. Biophys. Res. Commun, 2006; 350(4): 1056-1062. | |
| |
15. Rodrigo R., Bosco C. Oxidative stress and protective effects of polyphenols: comparative studies in human and rodent kidney. A review. Comp. Biochem. Physiol. C Toxicol. Pharmacol, 2006; 142(3-4): 317-327. | |
| |
16. Stitt-Cavanagh E., MacLeod L., Kennedy C. The podocyte in diabetic kidney disease. Scientific World Journal, 2009; 9: 1127-1139. | |
| |
17. Tikoo K., Singh K., Kabra D. et al. Change in histone H3 phosphorylation, MAP kinase p38, SIR 2 and p53 expression by resveratrol in preventing streptozotocin induced type I diabetic nephropathy. Free Radic. Res, 2008; 42(4): 397-404. | |
| |
18. Wagener F.A., Dekker D., Berden J.H. et al. The role of reactive oxygen species in apoptosis of the diabetic kidney. Apoptosis, 2009; 14(12): 1451-148. | |
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