THERMOMECHANOKINETICS OF VISCOELASTIC DEFORMATION OF SMOOTH MUSCLES IN THE RAT GASTROINTESTINAL TRACT. I. DYNAMIC PROPERTIES OF THE STRETCH IN STOMACH SMOOTH MUSKLES
DOI: http://dx.doi.org/10.30970/sbi.0602.213
Abstract
Functioning of the digestive system strongly depends on mechanical properties of smooth muscles that form the walls of the gastrointestinal tract organs. a quantitative analysis of temperature effects on the mechanokinetical curves „load-time” (at fixed loads) and „load-deformation” (with constant and gradual-increasing load) of rat stomach circular smooth muscles, in the work was carried out. Shows that the value of relative deformation [(L–Lp)/Lp] of muscle preparations – the parameter that depends on temperature; their high values are observed with a physiologically-relevant temperatures, whereas temperature shifts towards moderate cooling or heating it reduces. Increases in temperature up to 48°C had the opposite effect, it accompanied by decreasing of [(L–Lp)/Lp] at an average of 27% compared with the value that occurred in 37°C. by calculation of the relative change in stiffness coefficient it is shown that a moderate cooling (22°C) and heating (48°C) gastric smooth muscles causes it to increase by an average of 34% compared with their value in 37°C. However, the relatively low thermosensitivity of viscoelastic deformation of stomach smooth muscles indicates that in the physical sense in this process is predominate a passive component.
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