MODERN BREEDING AND MOLECULAR GENETIC APPROACHES TO ENHANCING WINTER BREAD WHEAT RESISTANCE TO BIOTIC AND ABIOTIC STRESSES UNDER GLOBAL CLIMATE CHANGE (REVIEW)

Yehor Kucherenko, Andrii Yarosh, Zoya Usova, Natalia Kuzmyshyna


DOI: http://dx.doi.org/10.30970/sbi.2003.894

Abstract


Background. Winter bread wheat (Triticum aestivum L.) is one of the world’s most important cereal crops, and its productivity is critical for global food security. Under ongoing climate change, the impact of biotic and abiotic stresses, including drought, high temperature, salinity, and frost, is increasing, leading to significant yield losses and reduced grain quality. This creates a strong need to integrate conventional breeding with modern molecular genetic and bioinformatics approaches to develop stress-resilient cultivars.
This review summarizes current breeding and molecular genetic strategies aimed at improving the resistance of winter bread wheat (T. aestivum L.) to biotic and abiotic stresses under changing climatic conditions. We analyze the applications of genetic markers, quantitative trait loci (QTL) mapping, genome-wide association studies (GWAS), genomic selection, and genome-editing technologies. Particular attention is given to integrating high-throughput phenotyping, molecular research, and digital tools into modern breeding pipelines, as well as to emerging sources of resistance and the development of an adaptive wheat gene pool.
Overall, this review highlights the importance of combining conventional breeding approaches with advanced molecular and genomic tools to enhance breeding efficiency. Such integration provides a coherent framework for developing next-generation wheat cultivars capable of maintaining stable yield performance under climate-related stress conditions and thereby contributing to global food security. The review also outlines key future research directions for improving breeding efficiency under increasing environmental variability.


Keywords


resistance breeding, climate change, adaptive potential, QTL analysis, marker-assisted selection (MAS), genomic selection

Full Text:

PDF

References


Ahad, A., Gul, A., Batool, T. S., Huda, N. U., Naseer, F., Salam, U. A., Salam, M. A., Ilyas, M., Unal, B. T., & Ozturk, M. (2023). Molecular and genetic perspectives of cold tolerance in wheat. Molecular Biology Reports, 50(8), 6997-7015. doi:10.1007/s11033-023-08584-1
CrossrefPubMed Google Scholar

Ahlawat, O. P., Yadav, D., Kashyap, P. L., Khippal, A., & Singh, G. (2022). Wheat endophytes and their potential role in managing abiotic stress under changing climate. Journal of Applied Microbiology, 132(4), 2501-2520. doi:10.1111/jam.15375
CrossrefPubMed Google Scholar

Ahres, M., Pálmai, T., Farkas, Z., Gulyás, Z., Soltész, A., Borbély, P., Tahmasebi, Z., Fowler, D. B., & Galiba, G. (2025). Investigating the impact of spring (Vrn-A1) and winter (vrn-A1) vernalization alleles on frost tolerance induced by light spectrum and low temperatures in different wheat backgrounds. Environmental and Experimental Botany, 229, 106079. doi:10.1016/j.envexpbot.2024.106079
CrossrefGoogle Scholar

Ali, N., Bais, A., Sangha, J. S., Cuthbert, R. D., & Ruan, Y. (2026). High-throughput UAV phenotyping for plot-level harvest index estimation in wheat fields. Current Plant Biology, 45, 100582. doi:10.1016/j.cpb.2026.100582
CrossrefGoogle Scholar

Babben, S., Schliephake, E., Janitza, P., Berner, T., Keilwagen, J., Koch, M., ... Perovic, D. (2018). Association genetics studies on frost tolerance in wheat (Triticum aestivum L.) reveal new highly conserved amino acid substitutions in CBF-A3, CBF-A15, VRN3 and PPD1 genes. BMC Genomics, 19, 409. doi:10.1186/s12864-018-4795-6
CrossrefPubMedPMCGoogle Scholar

Badawi, M., Danyluk, J., Boucho, B., Houde, M., & Sarhan, F. (2007). The CBF gene family in hexaploid wheat and its relationship to the phylogenetic complexity of cereal CBFs. Molecular Genetics and Genomics, 277(5), 533-554. doi:10.1007/s00438-006-0206-9
CrossrefPubMedPMCGoogle Scholar

Bazalii, V. V., Domaratskyi, Ye. O., & Kozlova, O. P. (2023). Breeding and genetic aspects of winter wheat on agroecological adaptability. Agrarian Innovations, 19, 120-126. doi:10.32848/agrar.innov.2023.19.19 (In Ukrainian)
CrossrefGoogle Scholar

Benitez-Alfonso, Y., Soanes, B. K., Zimba, S., Sinanaj, B., German, L., Sharma, V., ... Foyer, C. H. (2023). Enhancing climate change resilience in agricultural crops. Current Biology, 33(23), R1246-R1261. doi:10.1016/j.cub.2023.10.028
CrossrefPubMedGoogle Scholar

Bibi, F., & Rahman, A. (2023). An overview of climate change impacts on agriculture and their mitigation strategies. Agriculture, 13(8), 1508. doi:10.3390/agriculture13081508
CrossrefGoogle Scholar

Bolouri, P., Haliloğlu, K., Mohammadi, S. A., Türkoğlu, A., İlhan, E., Niedbała, G., Szulc, P., & Niazian, M. (2023). Identification of novel QTLs associated with frost tolerance in winter wheat (Triticum aestivum L.). Plants, 12(8), 1641. doi:10.3390/plants12081641
CrossrefPubMedPMCGoogle Scholar

Braun, K. (2025, April 23). Ukraine's once-booming grain industry teetering on being a war casualty. Reuters. https://www.reuters.com/markets/commodities/ukraines-once-booming-grain-industry-teetering-being-war-casualty-braun-2025-04-23

Budhlakoti, N., Kushwaha, A. K., Rai, A., Chaturvedi, K. K., Kumar, A., Pradhan, A. K., Kumar, U., Kumar, R. R., Juliana, P., Mishra, D. C., & Kumar, S. (2022). Genomic selection: а tool for accelerating the efficiency of molecular breeding for development of climate-resilient crops. Frontiers in Genetics, 13, 832153. doi:10.3389/fgene.2022.832153
CrossrefPubMedPMCGoogle Scholar

Buerstmayr, H., Ban, T., & Anderson, J. A. (2009). QTL mapping and marker-assisted selection for Fusarium head blight resistance in wheat: a review. Plant Breeding, 128(1), 1-26. doi:10.1111/j.1439-0523.2008.01550.x
CrossrefGoogle Scholar

Campos-Avelar, I., Montoya-Martínez, A. C., Villa-Rodríguez, E. D., Valenzuela-Ruiz, V., Ayala Zepeda, M., Parra-Cota, F. I., & de los Santos Villalobos, S. (2023). The mitigation of phytopathogens in wheat under current and future climate change scenarios: next-generation microbial inoculants. Sustainability, 15(21), 15250. doi:10.3390/su152115250
CrossrefGoogle Scholar

Campoli, C., Matus-Cádiz, M. A., Pozniak, C. J., Cattivelli, L., & Fowler, D. B. (2009). Comparative expression of Cbf genes in the Triticeae under different acclimation induction temperatures. Molecular Genetics and Genomics, 282(2), 141-152. doi:10.1007/s00438-009-0451-9
CrossrefPubMedPMCGoogle Scholar

Chang-Brahim, I., Koppensteiner, L. J., Beltrame, L., Bodner, G., Saranti, A., Salzinger, J., Fanta-Jende, P., Sulzbachner, C., Trognitz, F., Samad-Zamini, M., & Molin, E. M. (2024). Reviewing the essential roles of remote phenotyping, GWAS and explainable AI in practical marker-assisted selection for drought-tolerant winter wheat breeding. Frontiers in Plant Science, 15, 1319938. doi:10.3389/fpls.2024.1319938
CrossrefPubMedPMCGoogle Scholar

Chen, B., Tu, Y., An, J., Wu, S., Lin, C., & Gong, P. (2024). Quantification of losses in agriculture production in eastern Ukraine due to the Russia-Ukraine war. Communications Earth & Environment, 5, 336. doi:10.1038/s43247-024-01488-3
CrossrefGoogle Scholar

Chen, H., Su, Z., Tian, B., Hao, G., Trick, H. N., & Bai, G. (2022). TaHRC suppresses the calcium-mediated immune response and triggers wheat Fusarium head blight susceptibility. Plant Physiology, 190(3), 1566-1569. doi:10.1093/plphys/kiac352
CrossrefPubMedPMCGoogle Scholar

Chuhrii, H. A., Vyskub, R. S., Poplevko, V. I., Shults, P., & Sknypa, N. L. (2022). Scientific principles of selection of soft winter wheat varieties according to adaptive characteristics. Agrarian Innovations, 11, 60-67. doi:10.32848/agrar.innov.2022.11.8 (In Ukrainian)
CrossrefGoogle Scholar

Chugunkova, T. V., Pastukhova, N. L., Pirko, Y. V., & Blume, Y. B. (2025). Genetic basis of resistance to wheat yellow rust. Cytology and Genetics, 59(2), 186-196. doi:10.3103/s0095452725020033
CrossrefGoogle Scholar

Crossa, J., Pérez-Rodríguez, P., Cuevas, J., Montesinos-López, O., Jarquín, D., De Los Campos, G., ... & Varshney, R. K. (2017). Genomic selection in plant breeding: methods, models, and perspectives. Trends in Plant Science, 22(11), 961-975. doi:10.1016/j.tplants.2017.08.011
CrossrefPubMedGoogle Schola

Cuthbert, P. A., Somers, D. J., Thomas, J., Cloutier, S., & Brulé-Babel, A. (2006). Fine mapping Fhb1, a major gene controlling fusarium head blight resistance in bread wheat (Triticum aestivum L.). Theoretical and Applied Genetics, 112(8), 1465-1472. doi:10.1007/s00122-006-0249-7
CrossrefPubMedGoogle Scholar

Deininger, K., Ali, D. A., Kussul, N., Shelestov, A., Lemoine, G. & Yailimova, H. (2023). Quantifying war-induced crop losses in Ukraine in near real time to strengthen local and global food security. Food Policy, 115, 102418. doi:10.1016/j.foodpol.2023.102418
CrossrefGoogle Scholar

Demydov, O. A., Dubovyk, N. S., Kyrylenko, V. V., Gumeniuk, O. V., Siroshtan, A. A., Sabadyn, V. Y., ... Lashuk, S. O. (2024). Formation of productivity elements of winter wheat varieties depending on agrotechnical factors in the conditions of the central Forest-Steppe. Plant Varieties Studying and Protection, 20(2), 96-103. doi:10.21498/2518-1017.20.2.2024.304102 (In Ukrainian)
CrossrefGoogle Scholar

Domaratskyi, Ye. O., Bazalii, V. V., Pichura, V. I., Drobitko, A. V., & Potravka, L. O. (2023). Water-holding capacity and drought resistance of winter wheat depending on the variety composition under non-irrigated conditions of the Steppe zone. Agrarian Innovations, 21, 146-153. doi:10.32848/agrar.innov.2023.21.22 (In Ukrainian)
CrossrefGoogle Scholar

Fang, T., Lei, L., Li, G., Powers, C., Hunger, R. M., Carver, B. F., & Yan, L. (2020). Development and deployment of KASP markers for multiple alleles of Lr34 in wheat. Theoretical and Applied Genetics, 133(7), 2183-2195. doi:10.1007/s00122-020-03589-x
CrossrefPubMedPMCGoogle Scholar

Feng, J., Wang, L., Wu, Y., Luo, Q., Zhang, Y., Qiu, D., Han, J., Su, P., Yang, G., & He, G. (2019). TaSnRK2.9, a sucrose non-fermenting 1-related protein kinase gene, positively regulates plant response to drought and salt stress in transgenic tobacco. Frontiers in Plant Science, 9, 2003. doi:10.3389/fpls.2018.02003
CrossrefPubMedPMCGoogle Scholar

Ferrante, A., Cossani, C. M., Able, J. A., & Sadras, V. O. (2024). Yield response to frost in a set of historic wheat varieties. Field Crops Research, 310, 109336. doi:10.1016/j.fcr.2024.109336
CrossrefGoogle Scholar

Fouad, N., El-Zayat, E. M., Amr, D., El-Khishin, D. A., Abd-Elhalim, H. M., Hafez, A., Radwan, K. H., Hamwieh, A., & Tadesse, W. (2025). Characterizing wheat rhizosphere bacterial microbiome dynamics under salinity stress: insights from 16S rRNA metagenomics for enhancing stress tolerance. Plants, 14(7), 1033. doi:10.3390/plants14071033
CrossrefPubMedPMCGoogle Scholar

Food and Agriculture Organization of the United Nations. (2026, March 12). Ukraine: Country brief - Food security snapshot (GIEWS Country Brief). https://www.fao.org/giews/countrybrief/country.jsp?code=UKR

Gogna, A., Kamali, B., Wimmer, V., Schmidt, R. H., Rezaei, E. E., Eckhoff, W. M., Reif, J. C., & Zhao, Y. (2026). Predicting enviromically adapted varieties with big data. Genome Biology, 27(1), 3. doi:10.1186/s13059-025-03914-x
CrossrefPubMedPMCGoogle Scholar

Gołębiowska, G., Dyda, M., & Wajdzik, K. (2021). Quantitative trait loci and candidate genes associated with cold-acclimation and Microdochium nivale tolerance/susceptibility in winter triticale (× Triticosecale). Plants, 10(12), 2678. doi:10.3390/plants10122678
CrossrefPubMedPMCGoogle Scholar

Guo, X., Lv, L., Zhao, A., Zhao, W., Liu, Y., Li, Z., Li, H., & Chen, X. (2025). Integrated transcriptome and metabolome analysis revealed differential drought stress response mechanisms of wheat seedlings with varying drought tolerance. BMC Plant Biology, 25(1), 571. doi:10.1186/s12870-025-06603-w
CrossrefPubMedPMCGoogle Scholar

Guo, X., Zhang, P., & Yue, Y. (2024). Global wheat planting suitability under the 1.5 °C and 2 °C warming targets. Frontiers in Plant Science, 15, 1410388. doi:10.3389/fpls.2024.1410388
CrossrefPubMedPMCGoogle Scholar

Gupta, R., Anand, G., & Bar, M. (2023). Developmental phytohormones: key players in host-microbe interactions. Journal of Plant Growth Regulation, 42(12), 7330-7351. doi:10.1007/s00344-023-11030-y
CrossrefGoogle Scholar

Gusain, S., Joshi, S., & Joshi, R. (2023). Sensing, signalling, and regulatory mechanism of cold-stress tolerance in plants. Plant Physiology and Biochemistry, 197, 107646. doi:10.1016/j.plaphy.2023.107646
CrossrefPubMedGoogle Scholar

Han, J., Luo, Y., Zhang, Z., Xu, J., Chen, Y., Asseng, S., Jägermeyr, J., Müller, C., Olesen, J. E., Rötter, R., & Tao, F. (2025). Planting area and production decreased for winter-triticeae crops but increased for rapeseed in Ukraine with climatic impacts dominating. Geography and Sustainability, 6(2), 100226. doi:10.1016/j.geosus.2025.100226
CrossrefGoogle Scholar

Hao, Y., Pan, Y., Chen, W., Rashid, M. A. R., Li, M., Che, N., Duan, X., & Zhao, Y. (2023). Contribution of duplicated nucleotide-binding leucine-rich repeat (NLR) genes to wheat disease resistance. Plants, 12(15), 2794. doi:10.3390/plants12152794
CrossrefPubMedPMCGoogle Scholar

Huang, W., Li, X., Zhang, Y., Chen, Q., & Wang, L. (2024). Seasonal precipitation distribution determines ecosystem CO2 and H2O exchange by regulating spring soil water-salt dynamics in a brackish wetland. Functional Ecology, 38(1), 234-245. doi:10.1111/1365-2435.14617
CrossrefGoogle Scholar

Hussain, B., Akpınar, B. A., Alaux, M., Algharib, A. M., Sehgal, D., Ali, Z., ... Budak, H. (2022). Capturing wheat phenotypes at the genome level. Frontiers in Plant Science, 13, 851079. doi:10.3389/fpls.2022.851079
CrossrefPubMedPMCGoogle Scholar

Jeon, D., Choi, C., Park, J. H., Kang, C.-S., Kim, J. Y., & Kim, C. (2026). Genomic selection for multi-trait crop improvement in wheat (Triticum aestivum L.): a practical modeling approach. BMC Plant Biology, 26(1), 400. doi:10.1186/s12870-026-08258-7
CrossrefPubMedPMCGoogle Scholar

Jiang, B., Liu, Y., Niu, H., He, Y., Ma, D., & Li, Y. (2022). Mining the roles of wheat (Triticum aestivum) SnRK genes in biotic and abiotic responses. Frontiers in Plant Science, 13, 934226. doi:10.3389/fpls.2022.934226
CrossrefPubMedPMCGoogle Scholar

Kaushal, S., Gill, H. S., Billah, M. M., Khan, S. N., Halder, J., Bernardo, A., St. Amand, P., Bai, G., Glover, K., & Sehgal, S. K. (2024). Enhancing the potential of phenomic and genomic prediction in winter wheat breeding using high-throughput phenotyping and deep learning. Frontiers in Plant Science, 15, 1410249. doi:10.3389/fpls.2024.1410249
CrossrefPubMedPMCGoogle Scholar

Klymiuk, V., Yaniv, E., Huang, L., Raats, D., Fatiukha, A., Chen, S., ... Fahima, T. (2018). Cloning of the wheat Yr15 resistance gene sheds light on the plant tandem kinase-pseudokinase family. Nature Communications, 9(1), 3735. doi:10.1038/s41467-018-06138-9
CrossrefPubMedPMCGoogle Scholar

Konovalova, V. M., Tyshchenko, A. V., Bazalii, H. G., Fundirat, K. S., Tyshchenko, O. D., Reznichenko, N. D., & Konovalov, V. O. (2023). Analysis of winter wheat varieties for drought resistance in the conditions of the Steppe of Ukraine (Part 3 - years with different moisture supply). Agrarian Innovations, 22, 132-143. doi:10.32848/agrar.innov.2023.22.21
CrossrefGoogle Scholar

Kovalov, S. R. (2025). Variability of yield and ear productivity traits of soft winter wheat in the Northern Subzone of the Ukrainian Steppe. Agrology, 8(1), 34-39. doi:10.32819/202505
CrossrefGoogle Scholar

Krattinger, S. G., Lagudah, E. S., Spielmeyer, W., Singh, R. P., Huerta-Espino, J., McFadden, H., Bossolini, E., Selter, L. L., & Keller, B. (2009). A putative ABC transporter confers durable resistance to multiple fungal pathogens in wheat. Science, 323(5919), 1360-1363. doi:10.1126/science.1166453
CrossrefPubMedGoogle Scholar

Kruse, E. B., Carle, S. W., Wen, N., Skinner, D. Z., Murray, T. D., Garland-Campbell, K. A., & Carter, A. H. (2017). Genomic regions associated with tolerance to freezing stress and snow mold in winter wheat. G3: Genes, Genomes, Genetics, 7(3), 775-780. doi:10.1534/g3.116.037622
CrossrefPubMedPMCGoogle Scholar

Liu, J., Gock, A., Ramm, K., Stops, S., Phongkham, T., Norman, A., Eastwood, R., Stone, E., & Dillon, S. (2025). Incorporating gene expression and environment for genomic prediction in wheat. Frontiers in Plant Science, 16, 1506434. doi:10.3389/fpls.2025.1506434
CrossrefPubMedPMCGoogle Scholar

Liu, M., Wang, Z., Xiao, H. M., & Yang, Y. (2018). Characterization of TaDREB1 in wheat genotypes with different seed germination under osmotic stress. Hereditas, 155(1), 26. doi:10.1186/s41065-018-0064-6
CrossrefPubMedPMCGoogle Scholar

Liu, Q., Zhang, X., Su, Y. H., & Zhang, X. S. (2022). Genetic mechanisms of cold signaling in wheat (Triticum aestivum L.). Life, 12(5), 700. doi:10.3390/life12050700
CrossrefPubMedPMCGoogle Scholar

Lodhi, N., & Srivastava, R. (2025). Dynamics and malleability of plant DNA methylation during abiotic stresses. Epigenomes, 9(3), 31. doi:10.3390/epigenomes9030031
CrossrefPubMedPMCGoogle Scholar

Ma, G., Wang, H., Qi, K., Ma, L., Zhang, B., Zhang, Y., Jiang, H., Wu, X., & Qi, J. (2024). Isolation, characterization, and pathogenicity of Fusarium species causing crown rot of wheat. Frontiers in Microbiology, 15, 1405115. doi:10.3389/fmicb.2024.1405115
CrossrefPubMedPMCGoogle Scholar

Mahmood, Z., Ali, M., Mirza, J. I., Fayyaz, M., Majeed, K., Naeem, M. K., Aziz, A., Trethowan, R., Ogbonnaya, F. C., Quraishi, U. M., Hickey, L. T., Rasheed, A., & He, Z. (2022). Genome-wide association and genomic prediction for stripe rust resistance in synthetic-derived wheats. Frontiers in Plant Science, 13, 788593. doi:10.3389/fpls.2022.788593
CrossrefPubMedPMCGoogle Scholar

Mapuranga, J., Song, L., Zhao, J., Li, H., Zhang, N., & Yang, W. (2026). Advances in understanding and managing Fusarium crown rot in wheat and barley: pathogen biology, host resistance, and integrated management strategies. Plant Stress, 19, 101224. doi:10.1016/j.stress.2026.101224
CrossrefGoogle Scholar

Merrick, L. F., Herr, A. W., Sandhu, K. S., Lozada, D. N., & Carter, A. H. (2022). Utilizing genomic selection for wheat population development and improvement. Agronomy, 12(2), 522. doi:10.3390/agronomy12020522
CrossrefGoogle Scholar

Milec, Z., Strejčková, B., & Šafář, J. (2023). Contemplation on wheat vernalization. Frontiers in Plant Science, 13, 1093792. doi:10.3389/fpls.2022.1093792
CrossrefPubMedPMCGoogle Scholar

Miller, A. K., Galiba, G., & Dubcovsky, J. (2006). A cluster of 11 CBF transcription factors is located at the frost tolerance locus Fr-Am2 in Triticum monococcum. Molecular Genetics and Genomics, 275(2), 193-203. doi:10.1007/s00438-005-0076-6
CrossrefPubMedGoogle Scholar

Mondini, L., Nachit, M., & Pagnotta, M. A. (2012). Identification of SNP mutations in DREB1, HKT1, and WRKY1 genes involved in drought and salt stress tolerance in durum wheat (Triticum turgidum L. var. durum). OMICS: A Journal of Integrative Biology, 16(4). doi:10.1089/omi.2011.0081
CrossrefPubMedGoogle Scholar

Moskalets, V., Kotsyuba, S., Novak, Z., Kryzhanivskiy, V., & Yaremenko, O. (2023). Creation of source material by attracting different varieties of common winter wheat in breeding for adaptability, productivity, and grain quality. Scientific Horizons, 26(7), 66-78. doi:10.48077/scihor7.2023.66
CrossrefGoogle Scholar

Motomura, Y., Kobayashi, F., Iehisa, J. C. M., & Takumi, S. (2013). A major quantitative trait locus for cold-responsive gene expression is linked to frost-resistance gene Fr-A2 in common wheat. Journal of Plant Breeding and Genetics, 63(1), 58-67. doi:10.1270/jsbbs.63.58
CrossrefPubMedPMCGoogle Scholar

Nakashima, K., Yamaguchi-Shinozaki, K., & Shinozaki, K. (2014). The transcriptional regulatory network in the drought response and its crosstalk in abiotic stress responses including drought, cold, and heat. Frontiers in Plant Science, 5, 170. doi:10.3389/fpls.2014.00170
CrossrefPubMedPMCGoogle Scholar

Ngou, B. P. M., Jones, J. D. G., & Ding, P. (2022). Plant immune networks. Trends in Plant Science, 27(3), 255-273. doi:10.1016/j.tplants.2021.08.012
CrossrefPubMedGoogle Scholar

Nishanth, J. B., Gaddala, B., Suji, S., Fathima, P. R., Premkumar, A., Karavadi, B., Sorna Kumar, R. S. A., Iyyappan, J., & Dinakarkumar, Y. (2025). Epigenetic mechanisms regulating plant responses to abiotic stress and their role in developing climate resilient crops. Discover Plants, 2(1), 349. doi:10.1007/s44372-025-00432-9
CrossrefGoogle Scholar

Paux, E., Lafarge, S., Balfourier, F., Derory, J., Charmet, G., Alaux, M., Perchet, G., Bondoux, M., Baret, F., Barillot, R., Ravel, C., Sourdille, P., & Le Gouis, J. (2022). Breeding for economically and environmentally sustainable wheat varieties: an integrated approach from genomics to selection. Biology, 11(1), 149. doi:10.3390/biology11010149
CrossrefPubMedPMCGoogle Scholar

Polityuk, P. (2025, August 4). Exclusive: Ukraine eyes higher 2025 grain harvest, plans more winter wheat for 2026. Reuters. https://www.reuters.com/business/environment/ukraine-eyes-higher-2025-grain-harvest-plans-more-winter-wheat-2026-2025-08-04

Pu, L., Jin, Q., Cai, X., Qu, C., Zhang, J., Bai, X., Guo, J., Kang, Z., & Guo, J. (2025). Crown rot in wheat: pathogen biology, host responses, and management strategies. Stress Biology, 5(1), 52. doi:10.1007/s44154-025-00247-4
CrossrefPubMedPMCGoogle Scholar

Raza, A., Charagh, S., Najafi-Kakavand, S., Abbas, S., Shoaib, Y., Anwar, S., Sharifi, S., Lu, G., & Siddique, K. H. M. (2023). Role of phytohormones in regulating cold stress tolerance: physiological and molecular approaches for developing cold-smart crop plants. Plant Stress, 8, 100152. doi:10.1016/j.stress.2023.100152
CrossrefGoogle Scholar

Rehman, S. U., Wang, J., Chang, X., Zhang, X., Mao, X., & Jing, R. (2019). A wheat protein kinase gene TaSnRK2.9-5A associated with yield contributing traits. Theoretical and Applied Genetics, 132(4), 907-919. doi:10.1007/s00122-018-3247-7
CrossrefPubMedPMCGoogle Scholar

Robles-Zazueta, C. A., Pinto, F., Molero, G., Foulkes, M. J., Reynolds, M. P., & Murchie, E. H. (2022). Prediction of photosynthetic, biophysical, and biochemical traits in wheat canopies to reduce the phenotyping bottleneck. Frontiers in Plant Science, 13, 828451. doi:10.3389/fpls.2022.828451
CrossrefPubMedPMCGoogle Scholar

Sabir, K., Rose, T., Wittkop, B., Stahl, A., Snowdon, R. J., Ballvora, A., Friedt, W., Kage, H., Léon, J., Ordon, F., Stützel, H., Zetzsche, H., & Chen, T.-W. (2023). Stage-specific genotype-by-environment interactions determine yield components in wheat. Nature Plants, 9(10), 1688-1696. doi:10.1038/s41477-023-01516-8
CrossrefPubMedGoogle Scholar

Saintenac, C., Lee, W.-S., Cambon, F., Rudd, J. J., King, R. C., Marande, W., Powers, S. J., Bergès, H., Phillips, A. L., Uauy, C., Hammond-Kosack, K. E., Langin, T., & Kanyuka, K. (2018). Wheat receptor-kinase-like protein Stb6 controls gene-for-gene resistance to fungal pathogen Zymoseptoria tritici. Nature Genetics, 50(3), 368-374. doi:10.1038/s41588-018-0051-x
CrossrefPubMedGoogle Scholar

Schierenbeck, M., Alqudah, A. M., Thabet, S. G., Lohwasser, U., Simón, M. R., & Börner, A. (2023). Association mapping unravels the genetics controlling seedling drought stress tolerance in winter wheat. Frontiers in Plant Science, 14, 1061845. doi:10.3389/fpls.2023.1061845
CrossrefPubMedPMCGoogle Scholar

Sehgal, D., Dhakate, P., Ambreen, H., Shaik, K. H. B., Rathan, N. D., Anusha, N. M., Deshmukh, R., & Vikram, P. (2023). Wheat omics: advancements and opportunities. Plants, 12(3), 426. doi:10.3390/plants12030426
CrossrefPubMedPMCGoogle Scholar

Sertse, D., Bekele, W. A., & McCartney, C. A. (2026). Genomic insights into winter wheat breeding for severely cold climates. International Journal of Molecular Sciences, 27(3), 1568. doi:10.3390/ijms27031568
CrossrefPubMedPMCGoogle Scholar

Shakaliі, S. M., Bahan, A. V., Yurchenko, S. O., & Golovash, L. M. (2022). Influence of various winter wheat variety properties on productivity variability. Scientific Progress & Innovations, 1, 11-17. doi:10.31210/visnyk2022.01.01
CrossrefGoogle Scholar

Shenoda, J. E., Sanad, M. N. M. E., Rizkalla, A. A., Hussein, M. H., & El-Assal, S. (2026). Crosstalk of heat shock proteins and antioxidants with peroxisome biogenesis supports wheat thermotolerance. Scientific Reports, 16(1), 14700. doi:10.1038/s41598-026-48451-0
CrossrefPubMedPMCGoogle Scholar

Shoukat, M. R., Wang, J., Habib-ur-Rahman, M., Hui, X., Hoogenboom, G., & Yan, H. (2024). Adaptation strategies for winter wheat production at farmer fields under a changing climate: employing crop and multiple global climate models. Agricultural Systems, 220, 104066. doi:10.1016/j.agsy.2024.104066
CrossrefGoogle Scholar

Smith, M. E., Kavamura, V. N., Hughes, D., Mendes, R., Lund, G., Clark, I., & Mauchline, T. H. (2025). Uncovering functional deterioration in the rhizosphere microbiome associated with post-green revolution wheat cultivars. Environmental Microbiome, 20(1), 64. doi:10.1186/s40793-025-00723-4
CrossrefPubMedPMCGoogle Scholar

Soleimani, B., Lehnert, H., Babben, S., Keilwagen, J., Koch, M., Arana-Ceballos, F. A., Chesnokov, Y., Pshenichnikova, T., Schondelmaier, J., Ordon, F., Börner, A., & Perovic, D. (2022). Genome wide association study of frost tolerance in wheat. Scientific Reports, 12(1), 5275. doi:10.1038/s41598-022-08706-y
CrossrefPubMedPMCGoogle Scholar

Spychała, J., Tomkowiak, A., Noweiska, A., Bobrowska, R., Rychel-Bielska, S., Bocianowski, J., Wolko, Ł., Kowalczewski, P. Ł., Nowicki, M., & Kwiatek, M. T. (2024). Expression patterns of candidate genes for the Lr46/Yr29 "slow rust" locus in common wheat (Triticum aestivum L.) and associated miRNAs inform of the gene conferring the Puccinia triticina resistance trait. PLoS One, 19(9), e0309944. doi:10.1371/journal.pone.0309944
CrossrefPubMedPMCGoogle Scholar

Su, Z., Jin, S., Zhang, D., & Bai, G. (2018). Development and validation of diagnostic markers for Fhb1 region, a major QTL for Fusarium head blight resistance in wheat. Theoretical and Applied Genetics, 131(11), 2371-2380. doi:10.1007/s00122-018-3159-6
CrossrefPubMedGoogle Scholar

Su, Z., Bernardo, A., Tian, B., Chen, H., Wang, S., Ma, H., Cai, S., Liu, D., Zhang, D., Li, T., Trick, H., St. Amand, P., Yu, J., Zhang, Z., & Bai, G. (2019). A deletion mutation in TaHRC confers Fhb1 resistance to Fusarium head blight in wheat. Nature Genetics, 51(7), 1099-1105. doi:10.1038/s41588-019-0425-8
CrossrefPubMedGoogle Scholar

Tang, T., Ge, J., Shi, H., Wang, L., Cao, J., & Lee, X. (2025). Drought frequency, intensity, and exposure have increased due to historical land use and land cover changes. Communications Earth & Environment, 6(1), 398. doi:10.1038/s43247-025-02392-0
CrossrefGoogle Scholar

Thomsen, L. E., Zhao, Y., Avenhaus, U., Reif, J. C., & Gundala, R. R. (2026). Integrating genomic predictions into an applied Central European wheat breeding program. Theoretical and Applied Genetics, 139(2), 69. doi:10.1007/s00122-026-05175-z
CrossrefPubMedPMCGoogle Scholar

Tiwari, V. K., Saripalli, G., Sharma, P. K., & Poland, J. (2024). Wheat genomics: genomes, pangenomes, and beyond. Trends in Genetics, 40(11), 982-992. doi:10.1016/j.tig.2024.07.004
CrossrefPubMedGoogle Scholar

Tran, B.-L., Tseng, W.-C., & Chen, C.-C. (2025). Climate change impacts on crop yields across temperature rise thresholds and climate zones. Scientific Reports, 15(1), 23424. doi:10.1038/s41598-025-07405-8
CrossrefPubMedPMCGoogle Scholar

Tsega, A., & Mullualem, D. (2026). Machine learning for multi-omics data integration in crop improvement: a systematic review. BMC Bioinformatics, 27(1), 81. doi:10.1186/s12859-026-06438-8
CrossrefPubMedPMCGoogle Scholar

Vaitkevičiūtė, G., Chawade, A., Lillemo, M., Liatukas, Ž., Aleliūnas, A., & Armonienė, R. (2023). Genome-wide association analysis of freezing tolerance and winter hardiness in winter wheat of Nordic origin. Plants, 12(23), 4014. doi:10.3390/plants12234014
CrossrefPubMedPMCGoogle Scholar

Wang, H., Yang, B.-S., Xing, L.-W., Yang, S.-Y., Hao, S.-N., Zhang, H.-H., Yu, W.-K., Wan, X.-N., & Sun, G.-Z. (2026). Relationships between freeze tolerance and plant architecture in winter wheat during tillering stage. Frontiers in Plant Science, 17, 1745479. doi:10.3389/fpls.2026.1745479
CrossrefPubMedPMCGoogle Scholar

Wang, L., & Chang, C. (2024). Stomatal improvement for crop stress resistance. Journal of Experimental Botany, 75(7), 1823-1833. doi:10.1093/jxb/erad477
CrossrefPubMedGoogle Scholar

Wang, T., Tong, R., Yuan, Z., & Li, Y. (2026). Beyond QTL and GWAS: how deep learning, graph models, and multi-omics are reshaping plant genomic prediction analysis. Frontiers in Genetics, 17, 1783939. doi:10.3389/fgene.2026.1783939
CrossrefPubMedPMCGoogle Scholar

Wang, Y., Cheng, X., Shan, Q., Zhang, Y., Liu, J., Gao, C., & Qiu, J.-L. (2014). Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nature Biotechnology, 32(9), 947-951. doi:10.1038/nbt.2969
CrossrefPubMedGoogle Scholar

Wang, Y.-X., Yu, T.-F., Wang, C.-X., Wei, J.-T., Zhang, S.-X., Liu, Y.-W., Chen, J., Zhou, Y.-B., Chen, M., Ma, Y.-Z., Lan, J.-H., Zheng, J.-C., Li, F., & Xu, Z.-S. (2023). Heat shock protein TaHSP17.4, a TaHOP interactor in wheat, improves plant stress tolerance. International Journal of Biological Macromolecules, 246, 125694. doi:10.1016/j.ijbiomac.2023.125694
CrossrefPubMedGoogle Scholar

Waqas, M., Rasheed, A., & Peng, J. (2025). Wheat genomics frontiers for gene discovery and breeding applications. WheatOmics, 1(1), 3. doi:10.1007/s44412-025-00002-6
CrossrefGoogle Scholar

Whiting, R., Ficht, A., Chen, Y., Torkamaneh, D., Colasanti, J., & Lyons, E. M. (2025). Genome-wide association analysis of winter survival in a diverse Canadian winter wheat population. The Plant Genome, 18(3), e70091. doi:10.1002/tpg2.70091
CrossrefPubMedPMCGoogle Scholar

World Bank. (2025, February 25). World Bank says Ukraine's agricultural sector suffered $11.2B in direct war-related losses. Ukrinform. https://www.ukrinform.net/rubric-economy/3964402-world-bank-says-ukraines-agricultural-sector-suffered-112b-in-direct-warrelated-losses.html

Wójcik-Gront, E., Zieniuk, B., & Pawełkowicz, M. (2024). Harnessing AI-powered genomic research for sustainable crop improvement. Agriculture, 14(12), 2299. doi:10.3390/agriculture14122299
CrossrefGoogle Scholar

Wu, L., Yu, W., Cheng, C., Feng, L., Yan, J., Zheng, D., & Yang, F. (2024). Integrative indexes reveal the tolerance of winter wheat to different overwinter freezing injury. Frontiers in Plant Science, 15, 1419381. doi:10.3389/fpls.2024.1419381
CrossrefPubMedPMCGoogle Scholar

Würschum, T., Longin, C. F. H., Hahn, V., Tucker, M. R., & Leiser, W. L. (2017). Copy number variations of CBF genes at the Fr-A2 locus are essential components of winter hardiness in wheat. The Plant Journal, 89(4), 764-773. doi:10.1111/tpj.13424
CrossrefPubMedGoogle Scholar

Xie, X., Zhao, P., Zhang, Y., Ni, Z., Sun, Q., & Guo, W. (2026). Beyond data: artificial intelligence, knowledge graphs, and the next revolution in wheat breeding. Plant Communications, 7(5), 101841. doi:10.1016/j.xplc.2026.101841
CrossrefPubMedPMCGoogle Scholar

Xing, L., Hu, P., Liu, J., Witek, K., Zhou, S., Xu, J., ... Cao, A. (2018). Pm21 from Haynaldia villosa encodes a CC-NBS-LRR protein conferring powdery mildew resistance in wheat. Molecular Plant, 11(6), 874-878. doi:10.1016/j.molp.2018.02.013
CrossrefPubMedGoogle Scholar

Yarosh, A., Kucherenko, Y., Barylko, M., Usova, Z., & Vasylenko, A. (2024). Ecological plasticity of soft winter wheat varieties and resistance to snow mould pathogen (Microdochium nivale (Fr.) Samuels & I. C. Hallett). Scientific Horizons, 27(10), 31-42. doi:10.48077/scihor10.2024.31
CrossrefGoogle Scholar

Yarosh, A. V., Riabchun, V. K., & Riabchun, N. I. (2022). Adaptability of winter bread wheat by environmental plasticity and stability. Plant Breeding and Seed Production, 121, 75-83. doi:10.30835/2413-7510.2022.260998
CrossrefGoogle Scholar

Yaghoubi Khanghahi, M., AbdElgawad, H., Curci, M., Garrigues, R., Korany, S. M., Alsherif, E. A., Verbruggen, E., Spagnuolo, M., Addesso, R., Sofo, A., Beemster, G. T. S., & Crecchio, C. (2025). Transcriptomic, biochemical, and microbiome assessments into drought and salinity tolerance in durum wheat mediated by plant growth-promoting bacteria. Physiology and Molecular Biology of Plants, 31(12), 2121-2143. doi:10.1007/s12298-025-01686-z
CrossrefPubMedPMCGoogle Scholar

Yan, L., Loukoianov, A., Tranquilli, G., Helguera, M., & Dubcovsky, J. (2003). Positional cloning of the wheat vernalization gene VRN1. Proceedings of the National Academy of Sciences, 100(10), 6263-6268. doi:10.1073/pnas.0937399100
CrossrefPubMedPMCGoogle Scholar

Zaid, A., Singh, A., & Uddin, K. (2026). Epigenetic mechanism of abiotic stress responses in plants. Horticulture Advances, 4(1), 7. doi:10.1007/s44281-025-00096-1
CrossrefGoogle Scholar

Zeng, Z., Guo, C., Yan, X., Song, J., Wang, C., Xu, X., & Hao, Y. (2022). QTL mapping and KASP marker development for seed vigor related traits in common wheat. Frontiers in Plant Science, 13, 994973. doi:10.3389/fpls.2022.994973
CrossrefPubMedPMCGoogle Scholar

Zhang, H., Xue, X., Guo, J., Huang, Y., Dai, X., Li, T., Hu, J., Qu, Y., & Li, H. (2022). Association of the recessive allele vrn-D1 with winter frost tolerance in bread wheat. Frontiers in Plant Science, 13, 879768. doi:10.3389/fpls.2022.879768
CrossrefPubMedPMCGoogle Scholar

Zhang, Y., Zhou, S., Yu, Y., Wu, Q., Zang, Z., Li, D., Wang, J., Ma, X., & Li, X. (2026). Fusarium crown rot in wheat: advances in the biology, pathogenicity, and management of Fusarium pseudograminearum. WheatOmics, 2(1), 6. doi:10.1007/s44412-026-00009-7
CrossrefGoogle Scholar

Zhu, P., Kim, T., Jin, Z., Lin, C., Wang, X., Ciais, P., Mueller, N. D., Aghakouchak, A., Huang, J., Mulla, D., & Makowski, D. (2022). The critical benefits of snowpack insulation and snowmelt for winter wheat productivity. Nature Climate Change, 12(5), 485-490. doi:10.1038/s41558-022-01327-3
CrossrefGoogle Scholar


Refbacks

  • There are currently no refbacks.


Copyright (c) 2026 Yehor Kucherenko, Andrii Yarosh, Zoya Usova, Natalia Kuzmyshyna

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.