CADMIUM IN HUMAN AND ANIMAL ORGANISM. II. EFFECT ON FUNCTIONAL ACTIVITY OF ORGANS AND SYSTEMS

H. L. Antonyak; N. O. Babych; L. P. Biletska; N. E. Panas; Y. V. Zhylishchych

doi:10.30970/sbi.0403.110

CADMIUM IN HUMAN AND ANIMAL ORGANISM. II. EFFECT ON FUNCTIONAL ACTIVITY OF ORGANS AND SYSTEMS

H. L. Antonyak, N. O. Babych, L. P. Biletska, N. E. Panas, Y. V. Zhylishchych

DOI: http://dx.doi.org/10.30970/sbi.0403.110

Abstract

The analytical review of new data regarding the effects of Cadmium on human and animal organism are presented. The peculiarities of Cadmium impact on functional activities of excretory, respiratory, haematopoietic, immune and other systems have been analyzed. It is shown that under long-term intake Cadmium accumulates in the cells and exhibits cumulative toxicity causing pathological changes in tissues and organs (kidney, lung, bone, reproductive and endocrine organs). It is noted that the susceptibility of cells to Cadmium is dependent on the level of expression of metallothionein genes. Metabolic effects in vitally important organs under the intake of Cadmium are considered.

Keywords

Cadmium, toxicity, metabolism, nephropathy, osteoporosis, hematotoxicity

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References

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Biologichni Studii / Studia Biologica

CADMIUM IN HUMAN AND ANIMAL ORGANISM. II. EFFECT ON FUNCTIONAL ACTIVITY OF ORGANS AND SYSTEMS

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