INVESTIGATION OF CHEMICAL SUBSTANCES OF TERRESTRIAL ARTHROPODS
DOI: http://dx.doi.org/10.30970/sbi.1301.594
Abstract
Millions of Arthropods are inhabitants of the Earth and some biochemical products which they produce are valuable for human practice. The aim of this work was to summarize current information about chemical substances produced by Arthropods such as venoms, toxins and some other chemical compounds that may be used in practice. Today such products are obtained and purified using standard biochemical methods. In this article, the information about species of the terrestrial Arthropods – producers of substances acting on the nervous system and used in electrophysiological investigations is presented. Some versions of arthropods’ toxins classification and the table with Araneids toxins and effects they occur are suggested as well. Main attention was paid to some Araneidae venoms and toxins that block synaptic transmission in glutamatergic synapses. A review of chemical composition and some biophysical properties of such venoms and toxins was suggested and their chemical structures namely of toxins from spiders of Nephila family and toxins from A. lobata venom were described. Some biophysical properties of Araneidae venoms and toxins are characterized. Other components of Arthropods’ venoms were also observed. Contemporary applications of such chemical compounds in agriculture and in the environmental monitoring systems were considered as well. The obtained results evidence that the terrestrial Arthropods is a valuable source of chemical compounds for biophysical laboratories and their great potential has to attract more attention of investigators.
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1. Abe T., Miwa A. Effects of a spider toxin on the glutaminergic synapse of lobster muscle. J. Physiol., 1983; 389: 243-252. | |
| |
2. Akaike N., Kawai N., Kiskin N.I., Kljuchko E.M., Krishtal O. A., Tsyndrenko A.Ya. Spider toxin blocks excitatory amino acid responses in isolated hippocampal pyramidal neurons. Neurosci. Lett., 1987; 79: 326-330. | |
| |
3. Akhunov A., Chernetsky I.I., Sadykov A.S. Biochemical characteristics of some arthropods venoms of Central Asia. Dokl. AN USSR, 1985; 285(4): 1009-1011. (In Russian) | |
| |
4. Antonov S. M, Grishin E. V., Magazanik L. G., Shupliakov О. V., Vesselkin N. P., Volkova T.M. Argiopin blocks the glutamate responses and sensomotor transmission in motoneurones of isolated frog spinal cord. Neurosci. Lett., 1987; 83(1,2): 179-184. | |
| |
5. Aramaki Y., Yashuhara T., Higashijima T., Yoshioka M, Miwa A. Kawai N., Nakajima T. Chemical characterization of spider toxins JSTX and NSTX. Proc. Japan Academy, 1986; 62(9): 1012-1014. | |
| |
6. Ashe J.H., Cox C.L., Adams M.E. Argiotoxin 636 blocks excitatory synaptic transmission in rat hippocampal neurons. Brain Res., 1989; 480(1/2): 234-241. | |
| |
7. Atkinson P.K. Some studies or the oedematogenic action of the verom or funnel web spiders (Atrax species). Aust. J. Exp. Biol. Med. Sci., 1986; 64(5): 453-464. | |
| |
8. Bateman A., Boden P., Dell A., Duce I.R., Quicke D.L., Usherwood P.N.R. Postsynaptic block of a glutaminergic synapse by low molecular weight fraction of spider venom. Brain Res., 1985; 339(2): 237-244. | |
| |
9. Boden P., Bycroft B.W., Chabra S.R., Chiplin J., Crowley P.J., Grout R.J., King T.J., McDonald E., Rafferty P., Usherwood P.N.R. The action of natural and synthetic isomers of quisqualic acid at a well-defined glutamatergic synapse. Brain Res., 1986; 385(2): 205-211. | |
| |
10. Bowers C., Phillips H.S., Lee P., Jan I.N., Jan L.Y. Identification and purification of an irreversible presynaptic neurotoxin from the venom of the spider Hololena curta. Proc. Natl. Acad. Sci. USA, 1987; 84(10): 8506-8510. | |
| |
11. Branton W.D., Kolton L., Jan I. N., Jan L.I. Neurotoxins from Plectreurus spider venom are potent presynaptic blockers in Drosophyla. J. Neurosci., 1987; 7(12): 4195-4200. | |
| |
12. Budd T., Clinton P., Dell A., Duce I.R., Johnson S. J., Quicke D.L.J., Usherwood P.N.R., Usoh G. Isolation and characterisation of glutamate receptor antagonists from venoms of orb-web spiders. Brain Res., 1988; 448(2): 30-39. | |
| |
13. Catterall W. Neurotoxins as allosteric modifiers of voltage-sensitive sodium channels. In: Advances in cytopharmacology. New York: Raven Press, 1979: 305-316. | |
| |
14. Cavalieri M., D'Urso I., Lassa A., Pierdominici E., Robello H., Grusso A. Characterisation and some properties of the venom gland extract of a theriid spider (Steatoda paukulliana) frequently mistaken for black widow spider (Latrodectus tredecimguttatus). Toxicon, 1987; 25(9): 965-974. | |
| |
15. Chanturia A.N., Mironov S.L., Sokolov Yu.V. The energy profile of the channel formed by latrotoxin in bilayer phospholipid membrane. Ukr. Biochem. Journal, 1986; 58(1): 48-56. (In Russian) | |
| |
16. Chemistry and Pharmacology. The Alkaloids. (Ed.) G.A. Cordell, A. Brossi. USA: Academic Press, 1994: 280 p. | |
| |
17. Early S.L., Michaelis E.K. Presence of protein and glutamate as major constituents of the venom of the spider Araneus gemma. Toxicon, 1987; 25(4): 433-442. | |
| |
18. Elin E.A., Macedo V.F., Onoprienko V.V., Osokina N.E., Tikhomirova O.V. Synthesis of argiopin. Bioogr. Chemistry, 1988; 14(5): 704-706. (In Russian) | |
| |
19. Friedel T., Nentwig W. Immobilising and lethal effects of spider venoms on the cockroach and the common meal beetle. Toxicon, 1989; 27(3): 305-316. | |
| |
20. Fortschritte der Chemie organischer Naturstoffe. In: Progress in the Chemistry of Organic Natural Products. (Ed.) W. Herz, G.W. Kirby, R.E. Moore, W. Steglich, Ch. Tamm. USA: Springer Science & Business Media, 2012; 66: 332 p. | |
| |
21. Gration K.A.F., Clark R.B., Usherwood P.N.R. Three types of glutamate receptor on junktional membrane of locust muscle fibers. Brain Res., 1979; 171(2): 360-364. | |
| |
22. Grishin E.V., Volkova T.M., Arseniev A.S. Antagonists of glutamate receptors from the venom of Argiope lobata spider. Bioorganicheskaya chimia, 1988; 14(7): 883-892. (In Russian). | |
| |
23. Grishin E.V., Volkova T.M. Arsenyev A.S., Reshetova O.S., Onoprienko V.V., Magazanik L.G., Antonov S.M., Fedorova I.M. Structural and functional characteristics of argiopin - ion channel blocker from venom of spider Argiope lobata. Bioorganicheskaya chimia, 1986; 12(8): 1121-1124 (In Russian) | |
| |
24. Hagiwara K., Aramaki Y., Shimazaki K., Kawai N., Nakajima T. Iodinated Joro toxin (JSTX-3). Its structure and binding to the lobster neuromuscular synapse. Chem. Pharm. Bull., 1988; 36(3): 1233-1236. | |
| |
25. Haliwell J.V., Othman J.B., Pelchen-Mattheus A., Dolly J. O. Central action of dendrotoxin: selective reduction of transient K conductance in hippocampus and binding to localized acceptors. Proc. Natl. Acad. Sci. USA., 1986; 83: 493-497. | |
| |
26. Hashimoto Y., Endo Y., Shudo K., Aramaki Y., Kawai N., Nakajima T. Synthesis of spider toxin JSTX-3 and its analogs. Tetrah. Lett., 1987; 28(30): 3511-3514. | |
| |
27. Himmelreih N.G, Pivneva T.A., Lishko V.K., Ivanov A.P. On the calcium permeability of latrotoxin-induced synaptosomes. Ukr. Biochem. Journal, 1987; 59(2): 39-44. (In Russian) | |
| |
28. Jackson H., Usherwood F. N. R. Spider toxins as tools for dissecting elements of excitatory amino acids transmission. Trends In Neurosci., 1988; 11(6): 278-283. | |
| |
29. Jankovic J., Albanese A., Atassi M.Z., Dolly J.O., Hallett M., Mayer N.H. Botulinum Toxin E-Book: Therapeutic Clinical Practice and Science. USA: Elsevier Health Sciences, 2009. 512 p. | |
| |
30. Kawai N., Miwa A., Abe T. Spider venom contains specific receptor blocker of glutaminergic synapses. Brain Res., 1982; 247(1): 169-171. | |
| |
31. Kawai N., Miwa A., Abe T. Effect of spider toxin on glutaminergic synapses in the mammalian brain. Biomed. Res., 1982; 3(3): 353-355. | |
| |
32. Kawai N., Miwa A., Abe T. Blook of glutamate receptors by a spider toxin. In: Maridel P., DeFendis F.V. (Ed.) From Molecular Pharmacology to Behavior. New York: Raven Press, 1983: 30-34. | |
| |
33. Kawai N., Yamagishi S., Saito M, Furuya K. Blockade of synaptic transmission in the squid giant synapse by a spider toxin (JSTX). Brain Res., 1983; 278(2): 346-349. | |
| |
34. Kawai N., Miwa A., Saito M., Pan-How H., Yosioka M. Spider toxin (JSTX) action on the glutamate synapse. J. Physiol., 1984; 79(4): 228-231. | |
| |
35. Kerry C.J., Ramsey R.L., Sansom M.S.P., Usherwood P.N.R. Single channel studies of non-comretitive antagonism of a quisqualate sensitive glutamate receptor by argiotoxin636 - a fraction isolated from orb-web spider venom. Brain Res., 1988; 459(2): 312-327. | |
| |
36. Kiskin N.I., Klyuchko E.M., Kryshtal O.A., Tsyndrenko A.Ya., Akaike N., Kawai N. Blocking action of Nephila clavata spider toxin on ionic currents activated by glutamate and its agonists in isolated hippocampal neurons. Neurophysiology, 1989; 21(2): 110-116. | |
| |
37. Kits K.S., Pick T. Action of the polyamine β-philantotoxin on neuromuscular transmission in insects. Neuropharm., 1986; 25(10): 1089-1093. | |
| |
38. Klyuchko O.M. Information and computer technologies in biology and medicine. Kyiv: NAU-druk, 2008. 252 p. (In Ukrainian) | |
| |
39. Klyuchko O.M. Investigation and simulation of some antagonists influence on glutamate- and kainat-activated currents in neuronal membranes of the brain. In: Contemporary problems of biology, ecology and chemistry. Materials of III Intl. Sci. Conference. Zaporizzhia: Copy Art, 2012: 230 (In Ukrainian) | |
| |
40. Klyuchko O.M. Monitoring of influence on organisms of some carbohydrates environmental pollutants - derivatives of phenol and indole. In: Contemporary problems of biology, ecology and chemistry. Materials of IV Intl. Sci. Conference. Zaporizzhia: Copy Art, 2015: 87- 89. (In Ukrainian) | |
| |
41. Klyuchko O.M. Electronic expert systems for biology and medicine. Biotechnologia acta, 2018; 11(6): 5-28. | |
| |
42. Klyuchko O.M. Biotechnical information systems for monitoring of chemicals in environment: biophysical approach. Biotechnologia acta, 2019; 12(1): 5-28. | |
| |
43. Klyuchko О.М., Klyuchko Z.F. Use of technical bioinformation systems for ecological monitoring of environment pollution by toxic organic substances in ATO zone of Ukraine. In: Zoocenosis-2015. Biodiversity and role of animals in ecosystems. Materials of VІІІ Intl. Sci. Conference. Dnipro: Lira, 2015: 30-31. (In Ukrainian) | |
| |
44. Klyuchko О.М., Klyuchko Z.F. Investigation of ecological effects of pollutant substances - derivatives of phenol and indole. In: Zoocenosis-2017. Biodiversity and role of animals in ecosystems. Materials of ІX Intl. Sci. Conference. Dnipro: Lira, 2017: 12-13 . (In Ukrainian) | |
| |
45. Klyuchko O.M. Method of application of biotechnical monitoring system for bioindicators' accounting with biosensor and sub-system for optical registration. - Patent UA 129987 U, G01N33/00, C12Q 1/02, C12N 15/00. Priority: 27.04.2018, u201804662, Issued: 26.11.2018, Bull. 22, 11 p. (In Ukrainian) | |
| |
46. Klyuchko O.M. Method of cells' dissociation. Patent UA 130672 U, G01N 33/00, C12Q 1/02, C12N 15/00. Priority: 27.04.18, u201804668, Issued: 26.12.2018, Bull. 24, 7p. (In Ukrainian). | |
| |
47. Klyuchko O.M. Method of qualitative analysis of chemical substances. Patent UA 131016 U, G01N33/50, G01N21/78, C12Q 1/60. Priority: 11.05.2018, u201805174, Issued: 10.01.2019, Bull. 1, 9 p. (In Ukrainian) | |
| |
48. Klyuchko O.M.. Method for monitoring of chemicals influence on bioorganisms in few time intervals. Patent UA 134575 U; G01N33/00, C12N 15/00, A61P 39/00. Priority: 14.12.2018, u201812443, - Issued: 27.05.2019, Bull. 10, 10 p. (In Ukrainian). | |
| |
49. Klyuchko O.M., Biletsky A.Ya., Lizunov G.V., Shutko V.N. Method of electrical signals generating by bio-elements in technical hybrid system. Patent UA 134574 U; A01N 1/02, G01N 33/00, A61N 1/32, B82Y 30/00. Priority: 14.12.2018, u201812442, - Issued: 27.05.2019, Bull. 10, 10p. (In Ukrainian) | |
| |
50. Klyuchko O.M., Biletsky A.Ya., Lizunov G.V., Shutko V.N. Method for application of the system of large-scale monitoring of bioobjects with possibility of their radar control. Patent UA 134576 U; МПK G01N33/00, A61B 5/05, G01N 33/50, C12Q 1/02, G01S 13/00. Priority: 14.12.2018, u201812444, - Issued: 27.05.2019, Bull. 10, 10 p. (In Ukrainian) | |
| |
51. Klyuchko O.M., Biletsky A.Ya., Navrotskyi D.O. Method of bio-sensor test system application. Patent UA 129923 U, G01N33/00, G01N33/50, C12Q 1/02. Priority: 22.03.2018, u201802896, Issued: 26.11.2018, Bull. 22, 7 p. (In Ukrainian) | |
| |
52. Klyuchko O.M., Biletsky A.Ya., Navrotskyi D.O. Method of application of biotechnical monitoring system with biosensor (biosensor test system). - Patent UA 132245 U; G01N33/00. Priority: 23.03.2018 u201802893, Issued: 25.02.2014, Bull. 4, 7 p. (In Ukrainian) | |
| |
53. Klyuchko O.M., Biletsky A.Ya., Navrotskyi D.O. Method of application of biotechnical monitoring system with biosensor and sub-system for optical registration. - Patent UA 129922 U, G01N33/50. Priority: 22.03.2018, u201802894, Issued: 26.11.2018, Bull. 22, 10 p. (In Ukrainian) | |
| |
54. Klyuchko O.M., Biletsky A.Ya., Navrotskyi D. Method of application of biotechnical monitoring system with expert subsystem and biosensor. Patent UA 131863 U; G01N33/00, C12Q 1/02, C12N 15/00. Priority: 27.04.18, u201804663, Issued: 11.02.2019, Bull. 3, 7p. (In Ukrainian) | |
| |
55. Klyuchko O.M., Biletsky A.Ya., Navrotskyi D.A. Method of quantitative analysis of chemical substances. Patent UA 131524 U; G01N33/50, G01N21/78, C12Q 1/60G01N33/50, G01N21/78, C12Q 1/60. Priority: 11.05.2018, u201805175, Issued: 25.01.2019, Bull. 2, 10 p. (In Ukrainian) | |
| |
56. Klyuchko O.M., Biletsky A.Ya. Method of qualitative analysis of hydrocarbons with harmful and toxic effect on bioobjects. Patent UA 133676 U; G01N 33/50, G01N 21/78. Priority: 06.06.2018, u201806342, Issued: 25.04.2019, Bull. 8, 10 p. (In Ukrainian) | |
| |
57. Klyuchko O.M., Biletsky A.Ya. Method of qualitative analysis of chemical substances for the influence on electrical currents in bioobjects. Patent UA134142 U; G01N 33/50, G01N 21/78, C12Q 1/60. Priority: 06.06.2019, u201806345, Issued: 10.05.2019, Bull. 9, 10 p. (In Ukrainian) | |
| |
58. Kostyuk P.G., Kryshtal O.A. Mechanisms of electrical excitability of the nerve cell. M: Nauka, 1981. 208 p. (In Russian) | |
| |
59. Kusano Tomonobu, Suzuki Hideyuki. Polyamines: A Universal Molecular Nexus for Growth, Survival, and Specialized Metabolism. USA: Springer, 2015. 336 p. | |
| |
60. Lee C.Y. Resent advances in chemistry and pharmacology of snake toxins. In: Advances in Cytophormacology. New York: Raven Press, 1979: 1-16. | |
| |
61. Magazanik L.G., Antonov S.M., Gmiro V.E. Mechanisms of activation and blocking of the postsynaptic membrane sensitive to glutamate. Biological Membranes, 1984; 1(2): 130-140. (In Russian) | |
| |
62. Magazanik L.G., Antonov S.M., Fedorova I.M., Grishin E.V. The action of Agriope lobata spider venom and its low molecular weight component - argiopin on postsynaptic membranes. Biological Membranes, 1986; 3(12): 1204-1219. (In Russian) | |
| |
63. Magura I.S. Problems of electrical excitability of neuronal membrane. Kyiv: Naukova Dumka, 1981. 208 p. (In Russian) | |
| |
64. Martin M.F., Rochad H. Large scale purification of toxins from the venom of the scorpion Androctonus australis Hector. Toxicon, 1986; 24(11-12): 1131-1139. | |
| |
65. Martin M. F., Rochat H., Marchot P., Bougis P. E. Use of high performance liquid chromatography to demonstrate quantitative variation in components of venom from the scorpion Androctonus australis Hector. Toxicon, 1987; 25(5): 569-573. | |
| |
66. Matsuoka I., Syuto B., Kurinara K. , Kubo S. Cytotoxic action of Clostridium botulinum type C, toxin on neurons of central nervus system in dissociated culture. Jap. J. Med. Sci. Biol., 1986; 39(5-6): 247. | |
| |
67. Michaelis E.K., Michaelis M.L., Stormann T.M., Chittenden W.L., Grubbs R.D. Purification and molecular characterization of the brain synaptic membrane glutamate-binding protein. J. Neurochem., 1983; 30: 1742-1747. | |
| |
68. Michaelis E.K., Galton N. , Early S.L. Spider venoms inhibit L-glutamate binding to brain synaptic menbrane receptors. Proc. Natl. Acad. Sci. USA., 1984; 81: 5571-5574. | |
| |
69. Miwa A., Kawai N. Presynaptic glutamate receptor - possible involvement of K channel. Brain Res., 1986; 385(1): 161-164. | |
| |
70. Miwa A., Kawai N., Saito M., Pan-Hou H., Yosioka M. Effect of spider toxin (JSTX) on excitatory postsynaptic current at neuromuscular synapse of spiny lobster. J. Neurophys., 1987; 58(2): 216-220. | |
| |
71. Miwa A., Kawai N., Ui M. Pertussis toxin blocks presynaptic glutamate receptor - a novel 'glutamateB' receptor in lobster neuromuscular synapse. Brain Res., 1987; 416(1): 162-165. | |
| |
72. Mylecharane E.J., Spence I., Sheumack D.D., Claassens R. Howden M. E. M. Action of robustoxin, a neurotoxic polypeptide from the venom of the male funnel-web spider (Atrax robustus) in anaesthetized monkeys. Toxicon, 1989; 24(4): 481-492. | |
| |
73. Narahashi T. Modulation of neurve membrane sodium channe1s by neurotoxins. In: Advances in Cytopharmacology. New York: Raven Press, 1979: 293-304. | |
| |
74. Pan-Hou H., Suda Y. Molecular action mechanism of spider toxin on glutamate receptor: role of 2,4-dihydroxyphenylacetic acid in toxin molecule. Brain Res., 1987; 418(1): 198-200. | |
| |
75. Pan-Hou H., Suda Y., Sumi M, Yoshioka M., Kawai N. Inhibitory effect of 2,4-dihydroxyphenylacetylasparagine, a common moiety of spider toxins on glutamate binding to rat brain synaptic membranes. Neurosci. Lett., 1987; 81: 199-203. | |
| |
76. Pan-Hou H., Suda Y., Sumi M., Yoshioka M, Kawai N. A spider toxin (JSTX) inhibits L-glutanate uptake by rat brain synaptosomes. Brain Res., 1989; 476(2): 354-357. | |
| |
77. Piek T. Insect venoms and toxins. In: Kerkut G. A. (Ed.) Comprehensive Insect Physiology, Biochemistry and Pharmacology. Oxford: Pergamon Press, 1987; 11: 595-635. | |
| |
78. Saito M, Kawai N., Miwa A., Pan-Hou H., Yoshioka M. Spider toxin (JSTX) blocks glutamate synapse in hippocampal pyramidal neurons. Brain Res., 1985; 346(2): 397-399. | |
| |
79. Schmidt J., Blum M. S., Overal W.L. Comparative ensymology of venoms from stringing Hymenoptera . Toxicon, 1986; 24(9): 207-291. | |
| |
80. Shuplyakov O.V, Antonov S.M., Veselkin N.P., Magazanik L.G. The ability of argiopin to block glutamatergic synapses in the frog spinal cord. Zhurnal Evoliycion. Biohimii i Fiziologii, 1982; 23(2): 275-276. | |
| |
81. Skock V.I., Selianko A.A., Derckach V.A. Neuronal cholynoreceptors. M: Nauka, 1987. 343 p. (In Russian) | |
| |
82. Soloway S., Wilen S.H. Improved ferric chloride test for phenols. Anal. Chem., 1952; 24(6): 979-983. | |
| |
83. Tashmuhamedov B.A. Ion transport through biological membranes and the mechanism of physiologically active substances action. M: Nauka, 1985. 121p. (In Russian) | |
| |
84. Tashmuchamedov B.A., Makhmudova E.M., Usmanov P.B., Kazakov I. Reconstitution in bilayer lipid membranes of the Crab Potamon Transcaspicum spider venom sensitive glutamate receptors. Gen. Physiol. Biophys., 1985; 4(6): 625-630. | |
| |
85. Tashmuchamedov B.A., Makhmudova E.M., Usmanov P.B., Kazakov I., Atakuziev B.U. Isolation and reconstruction of glutamate receptors of insects on bilayer membranes. Uzbek. Biological Journal, 1983; 6: 57-58. (In Russian) | |
| |
86. Tashmuchamedov B.A., Usmanov P.B., Kazakov I., Kalikulov D. Yukelson L.Ya., Atakusiev B.U. Effects of different spider venoms on artificial and biological membranes. In: Hucho F., Ovchinnicov Y. A. (Ed.) Toxins as Tools in Neurochemistry. Berlin: Walter de Gruyter, 1983: 311-324. | |
| |
87. Teshima T., Wakamiya T., Aramaki Y., Nakajima T., Kawai N. Shiba T. Synthesis of a new neurotoxin NSTX-3 of Papua New Guinean spider. Tetrah. Lett., 1987; 28(30): 3509-3510. | |
| |
88. Tibballs J., Sutherland S. K., Duncan A.W. Effects of male Sydney funnel-web spider venom in a dog and cat. Austr. Vet. J., 1987; 64(2): 63-64. | |
| |
89. Tuychibaev M.U., Tashmuchamedov B.A., Magazanik L.G. New neurotoxin from the venom of the great hornet Vespa orientalis. Uzbek. Biological Journal, 1983; 6: 3-4. (In Russian) | |
| |
90. Ushkarev Yu.A., Grishin E.V. Karakurt neurotoxin and its interaction with the rat brain receptors. Bioorg. Chemistry, 1986; 12(1): 71-81 (In Russian) | |
| |
91. Usmanov P.B., Kalikulov D., Shadyeva N., Tashmuchamedov B. A. Action of Agriope lobata spider venom on glutamate and cholineric synapses. Dokl. AN USSR, 1983; 273(4): 1017-1018. (In Russian) | |
| |
92. Usmanov P.B., Kalikulov D., Nasledov G.A., Tashmuchamedov B.A. The effect of the venom of spider Segestria florentina on the mechanism of sodium channels inactivation. Biophysics, 1984; 30(4): 617-619. (In Russian) | |
| |
93. Usmanov P.B., Kalikulov D., Shadyeva N.G., Nenilin A.B. Tashmuchamedov B. A. Postsynaptic blocking of glutamatergic and cholinergic synapses as a common property of Araneidae spider venoins. Toxicon, 1985; 23(3): 528-553. | |
| |
94. Usmanov P. B., Tonkikh A.K., Shadyeva H., Sadykov A. A., Tashmuchamedov B. A. Effect of Agriope lobata spider venom and its components on the binding of L1 H1 glutamate to locust muscle membranes. Ukr. Biochem. Journal, 1988; 60(3): 78 - 81. (In Russian). | |
| |
95. Vycklický L., Krůšek J., Vycklický L., Vyskočil F. Spider venom of Araneus opens and desentitizes glutamate channels in chicken spinal cord neurons. Neurosci. Lett., 1986; 68: 227-231. | |
| |
96. Zlotkin E. Toxins derived from Arthropod venoms specially affecting insects. In: Kerkut G. A., Gilbert L. I. (Ed.) Comprehensive Insect Physiology, Biochemistry and Pharmacology. Oxford: Pergamon Press, 1985; 10: 499-546. | |
| |
97. Yoshioka M., Narai N., Pan-Hou H., Shimazaki K., Miwa A., Kawai N. Color development upon reaction of ferric ion with the toxin JSTX, a glutamate receptor blocker present in the venom gland of the spider Nephila clavata (Joro spider). Toxicon, 1988; 26(4): 414-416. | |
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