СИНТЕЗ 4-АМІНО-1-АРИЛПІРАЗОЛІВ НА ОСНОВІ ЕТИЛ 2‑ЦІАНО‑2‑(2‑АРИЛГІДРАЗИНІЛІДЕН)АЦЕТАТІВ

M. Barabash, M. Ostapiuk, Yu. Ostapiuk

Анотація


Описано метод отримання низки нових 3,5-дизаміщених 4-аміно-1‑арилпіразолів. Показано, що взаємодія етил 2-ціано-2-(2-арилгідразиніліден) ацетатів з галогенокетонами відбувається за наявності основи в умовах реакції Дікмана-Торпа. Етил 2-ціано-2-(2-арилгідразиніліден)ацетати одержано реакцією азосполучення під час взаємодії арилдіазонієвих солей з етил 2‑ціаноацетатом.

 

Ключові слова: 4-амінопіразоли, арендіазонію хлориди, реакція азосполучення, реакція Торпа-Циглера.

 


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DOI: http://dx.doi.org/10.30970/vch.6501.205

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