МЕТОДИ ОДЕРЖАННЯ ТА МОЖЛИВІ НАПРЯМИ ХІМІЧНОЇ МОДИФІКАЦІЇ ПОХІДНИХ 1,3,4-ОКСАДІАЗОЛУ (огляд)

M. Lelyukh, I. Chaban, V. Matiychuk, B. Zimenkovsky

Анотація


Проведено огляд літературних джерел, на основі якого систематизовано дані про методи одержання та можливі напрями хімічної модифікації гетероциклічних систем на основі 1,3,4-оксадіазолу. З’ясовано, що зазначений скафолд є одним із важливих гетероциклічних фрагментів, які розглядають як перспективні структурні матриці для конструювання нових лікоподібних молекул.

 

Ключові слова: методи одержання, похідні 1,3,4-оксадіазолу, хімічна модифікація реакція циклодегідратації, окисна циклізація.


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DOI: http://dx.doi.org/10.30970/vch.6002.256

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